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In Senegal, the authors assessed the efficacy and safety of a live attenuated influenza vaccine based on Russian-derived master donor viruses and licensed as a single dose. Live attenuated influenza vaccine was well tolerated in young children in Senegal, but did not provide protection against influenza. Further study in such populations, which might experience extended periods of influenza circulation, is warranted.
http://www.thelancet.com/journals/langlo/article/PIIS2214-109X(16)30201-7/fulltext
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