Alcohol use during pregnancy is the direct cause of fetal alcohol syndrome (FAS). The authors aimed to estimate the prevalence of alcohol use during pregnancy and FAS in the general population and, by linking these two indicators, estimate the number of pregnant women that consumed alcohol during pregnancy per one case of FAS. Alcohol use during pregnancy is common in many countries and as such, FAS is a relatively prevalent alcohol-related birth defect. More effective prevention strategies targeting alcohol use during pregnancy and surveillance of FAS are urgently needed.


  1. Gell, L, Ally, A, Buykx, P, Hope, A, and Meier, P. Alcohol's harm to others: an institute of alcohol studies reportInstitute of Alcohol Studies, University of Sheffield,Sheffield2015

  2. Kesmodel, U, Wisborg, K, Olsen, SF, Henriksen, TB, and Secher, NJ. Moderate alcohol intake during pregnancy and the risk of stillbirth and death in the first year of life. Am J Epidemiol2002155305–312

  3. Henriksen, TB, Hjollund, NH, Jensen, TK et al. Alcohol consumption at the time of conception and spontaneous abortion. Am J Epidemiol2004160661–667


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