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The objective was to determine whether low dose aspirin reduces the rate of spontaneous PTB in nulliparous women without medical co-morbidities. This is a secondary analysis of a randomized, placebo-controlled trial of low dose aspirin for prevention of preeclampsia in healthy, low-risk, nulliparous women. Low dose aspirin is associated with a substantial decrease in spontaneous PTB <34wks in healthy nulliparous women without co-morbidities. These findings suggest a new therapeutic option for PTB prevention that requires further study.
References
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