This article is part of the network’s archive of useful research information. This article is closed to new comments due to inactivity. We welcome new content which can be done by submitting an article for review or take part in discussions in an open topic or submit a blog post to take your discussions online.

Prior studies on the association between prenatal exposure to polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE) and child motor development have found contradicting results. Using data collected in the INUENDO cohort in Kharkiv (Ukraine), Warsaw (Poland) and Greenland (N = 1,103) between the years 2002 and 2012, teh authors in this study examined relations of prenatal exposure to 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p′-DDE) and 2,2′,4,4′,5,5′-hexachlorobiphenyl (CB-153) on motor development and developmental milestones; crawling, standing-up and walking. Findings suggest that In utero exposure to CB-153 and p,p′-DDE was not associated with parentally retrospectively assessed developmental milestones in infancy or parentally assessed motor skills at young school age. The use of a more sensitive outcome measure may be warranted if subtle effects should be identified.

http://www.biomedcentral.com/1471-2458/15/146

References

  1. van den Berg H, Zaim M, Yadav RS, Soares A, Ameneshewa B, Mnzava A, et al.: Global trends in the use of insecticides to control vector-borne diseases. Environ Health Perspect 2012, 120:577-82.

  2. Glynn A, Aune M, Darnerud PO, Cnattingius S, Bjerselius R, Becker W, et al.: Determinants of serum concentrations of organochlorine compounds in swedish pregnant women: a cross-sectional study. Environ Health. 2007, 6:2.

  3. Waliszewski SM, Aguirre AA, Infanzon RM, Siliceo J: Carry-over of persistent organochlorine pesticides through placenta to fetus. Salud Publica Mex 2000, 42:384-90

  4.  Dorea JG, Cruz-Granja AC, Lacayo-Romero ML, Cuadra-Leal J: Perinatal metabolism of dichlorodiphenyldichloroethylene in Nicaraguan mothers. Environ Res 2001, 86:229-37

  5. Czaja K, Ludwicki JK, Goralczyk K, Strucinski P: Organochlorine pesticides, HCB, and PCBs in human milk in Poland. Bull Environ Contam Toxicol 1997, 58:769-75

  6.  Gladen BC, Schecter AJ, Papke O, Shkyryak-Nyzhnyk ZA, Hryhorczuk DO, Little RE: Polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and coplanar polychlorinated biphenyls in breast milk from two cities in Ukraine. J Toxicol Environ Health A 1999, 58:119-27

Categories

Child Health  

Tags

Archive