Rubella remains an important pathogen worldwide, with roughly 100 000 cases of congenital rubella syndrome estimated to occur every year. This seminar present results regarding rubella control, elimination, and eradication policies, and a brief review of new laboratory diagnostics. Additionally, it provides novel information about rubella-containing vaccine immunogenetics and review the emerging evidence of interindividual variability in humoral and cell-mediated innate and adaptive immune responses to rubella-containing vaccine and their association with haplotypes and single-nucleotide polymorphisms across the human genome.

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2814%2960539-0/abstract

References

  1. Batra, Neetu. "Neurological disorders associated with Measles-Mumps-Rubella vaccination-a review." Science 3, no. 1 (2015): 81-86.

  2. Van Le, Son, Duc Hoang Le, Huong Thi Hoang, Ha Hoang, Nam Trung Nguyen, and Ha Hoang Chu. "Characterization of rubella virus genotypes among pregnant women in northern Vietnam, 2011–2013." Journal of medical virology 87, no. 2 (2015): 338-343.

  3. Uno, Yota, Tokio Uchiyama, Michiko Kurosawa, Branko Aleksic, and Norio Ozaki. "Early exposure to the combined measles–mumps–rubella vaccine and thimerosal-containing vaccines and risk of autism spectrum disorder." Vaccine (2015).

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