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This study aim to estimate the 10- and 20-year mortality from breast cancer following a diagnosis of DCIS and to establish whether the mortality rate is influenced by age at diagnosis, ethnicity, and initial treatment received. Findings suggest that important risk factors for death from breast cancer following a DCIS diagnosis include age at diagnosis and black ethnicity. The risk of death increases after a diagnosis of an ipsilateral second primary invasive breast cancer, but prevention of these recurrences by radiotherapy does not diminish breast cancer mortality at 10 years.

http://oncology.jamanetwork.com/article.aspx?articleid=2427491

References

  1. Ernster  VL, Ballard-Barbash  R, Barlow  WE,  et al.  Detection of ductal carcinoma in situ in women undergoing screening mammography. J Natl Cancer Inst. 2002;94(20):1546-1554.

  2. Brinton  LA, Sherman  ME, Carreon  JD, Anderson  WF.  Recent trends in breast cancer among younger women in the United States. J Natl Cancer Inst. 2008;100(22):1643-1648.

  3. Ernster  VL, Barclay  J, Kerlikowske  K, Wilkie  H, Ballard-Barbash  R.  Mortality among women with ductal carcinoma in situ of the breast in the population-based Surveillance, Epidemiology and End Results program. Arch Intern Med. 2000;160(7):953-958.

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