A Guide to Efficient Trial Management

This Guide to Efficient Trial Management, published by the Trial Manager's Network (UK) and available freely online, is a must for all trial managers or coordinators. This link is for the 6th Edition (2018)

Blended-learning for Clinical research nurses

Clinical research nurses are busy people! The Global Health Network Training Centre is therefore designed to offer snappy, practical 'how to' training courses that can be completed within 60-90 minutes, and more specialised modules can be taken over several sessions. However because some nurses don't find it easy to access a computer,

Health research capacity development in low and middle income countries: reality or rhetoric?

There has been steady progress in LMIC health research capacity, but major barriers to research persist and more empirical evidence on development strategies is required.

How to create and interpret epidemic curves

Epidemic curves are an important component of the public health and global health toolbox. Learn more about creating and interpretting them.

Clinical ResearchWorkshop - Malawi

How to report professional practice in nursing? A scoping review

Preparing for Genomic Medicine Nurse Training in Africa

Preparing for Genomic Medicine Nurse Training in Africa : A special report by Victoria Nembaware, Nicola Mulder and Raj Ramesar from H3ABioNet and the University of Cape Town Division of Human Genetics on 

Preparing for and Executing a Randomised Controlled Trial of Podoconiosis Treatment in Northern Ethiopia

This study highlights the utility of rapid ethical assessment prior to clinical trials involving complex procedures and concepts.

Understanding the Zika virus

U.S. efforts to combat the Zika virus in the US and abroad

Travel Medicine in the era of Chikungunya, Ebola, and Zika virus

Travel Medicine and Infectious Diseases have evolved rapidly in recent decades as outbreaks such as SARS, Avian Influenza, Ebola, MERS, Chikungunya, and Zika virus have demonstrated how quickly infections can cross international borders.

Comprehensive Public Health Degree Guide

Public Health Degrees.org is a comprehensive search engine designed for students who are interested in learning more about Public Health and Health Sciences programs around the United States.

Research Nurses workshops - India

Global Research Nurses is proud to announce skills sharing workshops at Mumbai and Gujarat, India in March 2016

This Week In Global Health (TWiGH) - Skills and Competencies for Public Health

Greg Martin talks about four areas of competencies needed to be effective in public health and global health. He places particular importance on management, leadership and governance.

Careers in Global Health

Looking for a job in global health? A 4 part series that takes a look at what you need to do to get your career in global health off to a good start.

eSeminar: Research papers that make a difference: discussing research waste, reproducibility and impact

Dr Iveta Seimer, Deputy Director of the UK EQUATOR Centre, discusses research waste, reproducibility, and how to use reporting guidelines to make an impact. Poor reporting seriously affects the integrity of health research literature and critically limits the use and impact of published studies.

ASLM: Reconstructing Laboratory Systems: How to Rebuild in Ebola-Affected Countries

"Burnout" in a clinical research trial environment

Annual Meeting of the South African Regional Faculty

Paper of the Month

Trusting rapid diagnostic tests in Zanzibar

Scientific title: Effectiveness of Malaria Rapid Diagnostic Tests in fever patients attending primary health care facilities in Zanzibar. Over the past decade, Zanzibar has adopted artemisinin-based combination therapy (ACT), long lasting insecticide treated nets and indoor residual spraying

Individual Participant Data (IPD) Meta-analyses of Randomised Controlled Trials: Guidance on Their Use

Systematic reviews involving the central collection and analysis of individual participant data (IPD) usually are larger-scale, international, collaborative projects that can bring about substantial improvements to the quantity and quality of data, give greater scope in the analyses, and provide more detailed and robust results. Following this step-by-step guide will help reviewers and users of IPD meta-analyses to understand them better and recognise those that are well designed and conducted and so help ensure that policy, practice, and research are informed by robust evidence about the effects of interventions.

Statistics from the Beginning

This article provides a helpful introduction to statistics as it relates to clinical research, explaining common terms and theories with examples and case studies. Powerpoint presentation also attached for further explanation.

Studies Within a Trial or Review

The SWAT and SWAR programme is identifying issues about the methods of trials and systematic reviews about which there is sufficient uncertainty to justify research to support well-informed decision making about future designs and choices.

A Guide to Grant Writing (available in English and Spanish)

Grant applications differ substantially depending on the individual funding organisation, and each funding organisation has its own organisational aims, which are important to understand when you are considering which grant to apply to. In this article we provide practical tips and information for writing grant applications, which can be applied to grant applications of all sorts, from fellowships to large funding applications.

The challenges facing malaria research

In this video, Professor Theonest Mutabingwa discusses the two key challenges that face developing countries to progress their malaria research.

Unravelling My Role as a Research Nurse

Joby George discusses his role as a research nurse based in India; what is involved, educational oprtions available, and what's important to him.

PERCH (Pneumonia Etiology Research for Child Health)

In this seminar from January 2014, Dr Jane Crawley talks about clinical standardisation in PERCH (Pneumonia Etiology Research for Child Health), a large case-control study of the causes of and risk factors for severe pneumonia.

How to prepare for a job interview and predict the questions you’ll be asked

Job interviews can be intimidating, but simply preparing well can make the difference between succeeding or failing, regardless of how nervous you are. In this article we pull together advice on how to prepare for job interviews and how to know what questions you’ll be asked. 

The transformation of the science cohort in South Africa

Professor Bongani M Mayosi from the Department of Medicine, Groote Schuur Hospital & University of Cape Town describes the transofmation of the science cohort in South Africa.

Managing clinical trials

Managing clinical trials, of whatever size and complexity, requires efficient trial management. Trials fail because tried and tested systems handed down through apprenticeships have not been documented, evaluated or published to guide new trialists starting out in this important field.

Workshop report: 'Recent Trends and Career Development in Clinical Research in India' - 19 Nov 2014

A workshop on “Recent Trends and Career Development in Clinical Research –INDIA”, was organized at Bhaskara Auditorium on 19th November 2014 by SAMSKARA, a Non Profit Organization based at Hyderabad and The Global Health Network for the first time in Telangana.   

Contribution of respiratory tract infections to child deaths: a data linkage study

Respiratory tract infections (RTIs) are an important cause of death in children, and often contribute to the terminal decline in children with chronic conditions. RTIs are often underrecorded as the underlying cause of death; therefore the overall contribution of RTIs to child deaths and the potential preventability of RTI-related deaths have not been adequately quantified. The authors in this study conclude that RTI-related deaths have not declined in the last decade among children in England, except in infants. Targeted strategies to prevent the winter excess of RTIs and to treat RTIs in children, particularly children with chronic conditions, may reduce RTI-related deaths.    

Ebola PPE guidelines

Ebola PPE guidelines - urgent need to revise WHO and CDC guidelines. This video shows an excerpt from keynote address 'The fuss about face masks', Professor Raina MacIntyre from the School of Public Health and Community Medicine, UNSW Australia.

Seven principles for strengthening research capacity in low- and middle-income countries: simple ideas in a complex world

This good practice document of the ESSENCE on Health Research initiative is designed to provide broad guidance on how best to strengthen research capacity with the maximum possible benefit. 

Writing and Publishing in Research: AuthorAid

AuthorAid is a great online tool whose aim is to support developing country researchers in publishing their work.

Five keys to improving research costing in low- and middle-income countries

ESSENCE on Health Research have created a good practice document on research costing. It includes a review of the funding practices related to the definition and funding of direct and indirect costs. 

Implementation Research in Health: A Practical Guide from the WHO

This guide, developed by the WHO and released in December 2013, aims to facilitate implementation research in LMICs.

A template for writing a research protocol

3 workshops in South India co-hosted by Global Research Nurses' network

An account of 3 skills sharing workshops in South India.

PRISMA for Abstracts: Reporting Systematic Reviews in Journal and Conference Abstracts

Despite published guidance on writing the abstract in the PRISMA Statement guiding the reporting of systematic reviews in general and elsewhere, evaluations show that reporting of systematic reviews in journal and conference abstracts is poor. Teh authors developed consensus-based reporting guidelines as an extension to the PRISMA Statement on good reporting of systematic reviews and meta-analyses in abstracts.

Critical issues in conducting non-commercially sponsored clinical research in South Africa: Meeting report 1st Feb 2013

On 1st February 2013, Global Health Trials Southern African Regional Faculy held the first of its Clinical Trials Skills-Sharing Workshops in South Africa, hosted by the University of Cape Town. Here you can find the presentations from the day.

Clinical Trials in East Africa: a One-Day Skills Sharing Workshop Report

Report on a one-day skills sharing workshop for improved clinical trials and research in East Africa, hosted by UVRI/MRC, EACCR and Global Health Trials and held on 15th February 2013.

Guidelines for an Integrated Approach to the Nutritional care of HIV-infected children

We share the WHO 2009 guideline that provides a framework for integrating nutrition support into the routine care of HIV-infected children (6 months-14 years). HIV-infected children deserve special attention because of their additional needs to ensure growth and development and their dependency on adults for adequate care including nutrition care and support for treatment. Vertical implementation of HIV programmes, such as PMTCT and ART, have resulted in missed opportunities to gain synergy with other existing services.

Community based supplementary feeding for promoting child growth-The Guideline

HIV and Infant Feeding-The Guidelines

Previously we have shared the guidelines pertaining to the early initiation and continuation of breast feeding and complementary feeding for newborns and infants. However there are concerns regarding breast feeding for women living with HIV. In particular, evidence has been reported that antiretroviral (ARV) interventions to either the HIV-infected mother or HIV-exposed infant can significantly reduce the risk of postnatal transmission of HIV through breastfeeding. This evidence has major implications for how women living with HIV might feed their infants, and how health workers should counsel these mothers. In light of this, the World Health Organization (WHO) commenced a guideline development process, culminating in a Guideline Development Group meeting in Geneva on 22–23 October 2009. We share here the revised guidelines by WHO for principles and recommendations for infant feeding inthe context of HIV.

Research Reporting Criteria

Research reporting guidelines are standard statements that provide guidance on how to report research methodology and findings. These are in the form of checklists, flow diagrams or texts. Most of the biomedical journals require authors to comply with these guidelines. Guidelines are available for reporting various study designs:

• CONSORT Statement (reporting of randomized controlled trials)
• STARD (reporting of diagnostic accuracy studies)
• STROBE (reporting of observational studies in epidemiology)
• PRISMA (reporting of systematic reviews)
• MOOSE (reporting of meta-analyses of observational studies)

A gold standard example of running a trial in Africa

We present this clinical trial as a gold standard example. This study addressed a key question in the management of severely ill children. It was conducted to a very high standard across 3 African countries. This article links to a short film that explains how this trial can be an example to all researchers in resource-limited settings and shows that research can and should be done.

A general introduction to Biomedical Research Ethics

This article was written by a researcher from Sri Lanka and presents a very helpful overview on Biomedical Ethics. This article will be helpful to all levels of research staff and others who might want an accessible overview

Safety Reporting

Considerations for pharmacovigilance and safety reporting.